Urticaria pigmentosa is an extremely rare disease that can cause damage to the skin as well as other parts of the body. An excess of inflammatory mast cells cause the disease by activating histamines, which produce redness, swelling, and itchiness in the affected area.
Urticaria pigmentosa occurs more commonly in children, and most often presents itself during infancy or early childhood. Adults who develop urticarial pigmentosa are more likely to experience the disease through the ages of 30 to 49 years.
Treatment of Urticaria pigmentosa includes prescription medication such as antihistamines, photochemotherapy, high potency topical steroids, and mast cell stabilizers.